Successful reversal of sleep apnoea syndrome following treatment for acromegaly, confirmed by polygraphic studies.
نویسندگان
چکیده
A patient with acromegaly was shown to have obstructive sleep apnoea by polygraphic recordings. Following successful hypophysectomy, further recordings demonstrated resolution of obstructive sleep apnoea.
منابع مشابه
Relief of sleep apnoea after treatment of acromegaly: report of three cases and review of the literature.
Sleep apnoea syndrome (SAS) is common in acromegalic patients. Occasionally, the relief of apnoeas after treatment of the acromegaly has been documented. We report the cases of three patients with acromegaly and severe obstructive sleep apnoea, who demonstrated a manifest improvement (respiratory disturbance index (RDI) <20) after treatment with octreotide, indicating that this drug may be effe...
متن کاملEffects of octreotide on sleep apnoea and tongue volume (magnetic resonance imaging) in patients with acromegaly.
OBJECTIVES Sleep apnoea has been consistently reported to occur in acromegaly. Both obstructive apnoeas, in which apnoeas are due to intermittent obstruction of the upper airways, as well as central apnoeas are known to occur. Because the relationship between disease activity and severity of sleep apnoea is currently unclear, we have performed a prospective study to address this issue. DESIGN...
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The treatment of acromegaly and hyperprolactinaemia has been improved by the availability of effective and well-tolerated slow-release somatostatin analogues and dopamine agonists with long-lasting activity, such as cabergoline. The use of these drugs has extended the possibility of treatment to patients who would have responded poorly to the previously available compounds, such as octreotide o...
متن کاملPrimary sleep apnoea syndrome.
Polygraphic study in 18 men with the sleep apnoea syndrome showed central, upper airway obstructive, and mixed apnoeas. Fifty per cent of the total apnoea time was central, 33% was obstructive, and 17% was mixed. Apnoeic episodes were accompanied by oxygen desaturation, relative bradycardia and hypotonia of orofacial muscles innervated by ponto-medullary neurons. During regular breathing these ...
متن کاملObstructive sleep apnoea in acromegaly: the role of craniofacial changes.
Obstructive sleep apnoea (OSA) is due to craniofacial changes and acromegaly. The question addressed by this study was whether growth hormone (GH) induced craniofacial changes might explain persisting OSA despite endocrine inactivity in acromegaly. Nineteen patients treated for acromegaly were examined cephalometrically for craniofacial changes and polysomnographically for OSA. Twelve patients ...
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عنوان ژورنال:
- Postgraduate medical journal
دوره 64 758 شماره
صفحات -
تاریخ انتشار 1988